8EV7
Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs
This is a non-PDB format compatible entry.
Summary for 8EV7
Entry DOI | 10.2210/pdb8ev7/pdb |
Descriptor | 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (60 entities in total) |
Functional Keywords | kanamycin, antibiotic, aminoglycoside, 70s ribosome, inhibitor, trna, ribosome |
Biological source | Escherichia coli More |
Total number of polymer chains | 112 |
Total formula weight | 4560660.35 |
Authors | Seely, S.M.,Gagnon, M.G. (deposition date: 2022-10-19, release date: 2023-08-09, Last modification date: 2023-11-15) |
Primary citation | Seely, S.M.,Parajuli, N.P.,De Tarafder, A.,Ge, X.,Sanyal, S.,Gagnon, M.G. Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14:4666-4666, 2023 Cited by PubMed: 37537169DOI: 10.1038/s41467-023-40416-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
Download full validation report