8ET2
CryoEM structure of the GSDMB pore
Summary for 8ET2
Entry DOI | 10.2210/pdb8et2/pdb |
EMDB information | 28584 |
Descriptor | Isoform 1 of Gasdermin-B (1 entity in total) |
Functional Keywords | pore-forming protein, gsdmb, pyroptosis, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 24 |
Total formula weight | 1124358.00 |
Authors | |
Primary citation | Wang, C.,Shivcharan, S.,Tian, T.,Wright, S.,Ma, D.,Chang, J.,Li, K.,Song, K.,Xu, C.,Rathinam, V.A.,Ruan, J. Structural basis for GSDMB pore formation and its targeting by IpaH7.8. Nature, 616:590-597, 2023 Cited by PubMed: 36991122DOI: 10.1038/s41586-023-05832-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.96 Å) |
Structure validation
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