8ES9

CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4

Summary for 8ES9

Entry DOI	10.2210/pdb8es9/pdb
EMDB information	28570 28571 28572 28573 28574
Descriptor	PN45428 TCR alpha chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
Functional Keywords	tcr, receptor, membrane protein, cd3, mhc, hla, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	11
Total formula weight	240267.21
Authors	Saotome, K.,Franklin, M.C. (deposition date: 2022-10-13, release date: 2023-05-03, Last modification date: 2024-05-01)
Primary citation	Saotome, K.,Dudgeon, D.,Colotti, K.,Moore, M.J.,Jones, J.,Zhou, Y.,Rafique, A.,Yancopoulos, G.D.,Murphy, A.J.,Lin, J.C.,Olson, W.C.,Franklin, M.C. Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14:2401-2401, 2023 Cited by PubMed: 37100770 DOI: 10.1038/s41467-023-37532-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.25 Å)

Structure validation