8ES8

CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239)

8ES8 の概要

• エントリーDOI: 10.2210/pdb8es8/pdb
• EMDBエントリー: 28570 28571 28572 28573 28574
• 分子名称: T-cell surface glycoprotein CD3 zeta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• 機能のキーワード: tcr, membrane protein, cd3, hla, mhc, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 11
• 化学式量合計: 242046.00

構造登録者

Saotome, K.,Franklin, M.C. (登録日: 2022-10-13, 公開日: 2023-05-03, 最終更新日: 2024-05-01)

• 主引用文献: Saotome, K.,Dudgeon, D.,Colotti, K.,Moore, M.J.,Jones, J.,Zhou, Y.,Rafique, A.,Yancopoulos, G.D.,Murphy, A.J.,Lin, J.C.,Olson, W.C.,Franklin, M.C.; Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.; Nat Commun, 14:2401-2401, 2023; PubMed: 37100770; DOI: 10.1038/s41467-023-37532-7

実験手法

ELECTRON MICROSCOPY (2.65 Å)