8EQ4

Human PAC in nanodisc at pH 4.0 with PI(4,5)P2 diC8

This is a non-PDB format compatible entry.

Summary for 8EQ4

• Entry DOI: 10.2210/pdb8eq4/pdb
• EMDB information: 28535
• Descriptor: Proton-activated chloride channel, 2-acetamido-2-deoxy-beta-D-glucopyranose, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (3 entities in total)
• Functional Keywords: pac, tmem206, asor, paorac, ion channels, chloride channel, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 125170.34

Authors

Ruan, Z.,Lu, W. (deposition date: 2022-10-07, release date: 2023-02-01)

• Primary citation: Mihaljevic, L.,Ruan, Z.,Osei-Owusu, J.,Lu, W.,Qiu, Z.; Inhibition of the proton-activated chloride channel PAC by PIP 2.; Elife, 12:-, 2023; PubMed: 36633397; DOI: 10.7554/eLife.83935

Experimental method

ELECTRON MICROSCOPY (2.71 Å)