8EOP

Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state

8EOP の概要

• エントリーDOI: 10.2210/pdb8eop/pdb
• EMDBエントリー: 28451
• 分子名称: Phospholipid-transporting ATPase ABCA7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: abc transporter, lipid transporter, abc exporter, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 237997.77

構造登録者

Alam, A.,Le, L.T.M.,Thompson, J.R. (登録日: 2022-10-04, 公開日: 2022-12-21, 最終更新日: 2023-02-15)

• 主引用文献: Le, L.T.M.,Thompson, J.R.,Dehghani-Ghahnaviyeh, S.,Pant, S.,Dang, P.X.,French, J.B.,Kanikeyo, T.,Tajkhorshid, E.,Alam, A.; Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.; Embo J., 42:e111065-e111065, 2023; PubMed: 36484366; DOI: 10.15252/embj.2022111065

実験手法

ELECTRON MICROSCOPY (3.7 Å)