8EM3
Carbonic Anhydrase II in complex with the diaryl urea molecule J2
Summary for 8EM3
Entry DOI | 10.2210/pdb8em3/pdb |
Descriptor | Carbonic anhydrase 2, 4-[(3-methoxyphenyl)carbamamido]benzene-1-sulfonamide, ZINC ION, ... (4 entities in total) |
Functional Keywords | inhibitor, caii, metal binding protein, lyase-inhibitor complex, lyase/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 29675.82 |
Authors | |
Primary citation | Debnath, J.,Keshamasetthy, D.,Combs, J.,Leon, K.,McKenna, R. Prospective Diaryl urea: Prevent growth of breast cancer cells by inhibition and down-regulation of Carbonic Anhydrase IX. To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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