8EM3

Carbonic Anhydrase II in complex with the diaryl urea molecule J2

Summary for 8EM3

• Entry DOI: 10.2210/pdb8em3/pdb
• Descriptor: Carbonic anhydrase 2, 4-[(3-methoxyphenyl)carbamamido]benzene-1-sulfonamide, ZINC ION, ... (4 entities in total)
• Functional Keywords: inhibitor, caii, metal binding protein, lyase-inhibitor complex, lyase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 29675.82

Authors

Combs, J.,McKenna, R. (deposition date: 2022-09-26, release date: 2023-09-27)

• Primary citation: Debnath, J.,Keshamasetthy, D.,Combs, J.,Leon, K.,McKenna, R.; Prospective Diaryl urea: Prevent growth of breast cancer cells by inhibition and down-regulation of Carbonic Anhydrase IX.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)