8EK9
Crystal structure of the class A carbapenemase CRH-1 in complex with avibactam at 1.4 Angstrom resolution
Summary for 8EK9
| Entry DOI | 10.2210/pdb8ek9/pdb |
| Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total) |
| Functional Keywords | class a carbapenemase, environmental lactamase, chromobacterium, dbo inhibitor, antimicrobial protein |
| Biological source | Chromobacterium haemolyticum |
| Total number of polymer chains | 1 |
| Total formula weight | 28952.84 |
| Authors | Power, P.,Brunetti, F.,Ghiglione, B.,Guardabassi, L.,Gutkind, G.,Klinke, S. (deposition date: 2022-09-20, release date: 2023-05-31, Last modification date: 2023-10-25) |
| Primary citation | Brunetti, F.,Ghiglione, B.,Gudeta, D.D.,Gutkind, G.,Guardabassi, L.,Klinke, S.,Power, P. Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC beta-Lactamases. Antimicrob.Agents Chemother., 67:e0006123-e0006123, 2023 Cited by PubMed: 37272821DOI: 10.1128/aac.00061-23 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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