8EJS

Kelch domain of human KEAP1 bound to Nrf2 linear peptide, Ac-(BAla)DPETGE-NH2

Summary for 8EJS

Entry DOI	10.2210/pdb8ejs/pdb
Descriptor	Kelch-like ECH-associated protein 1, Peptide from Nuclear factor erythroid 2-related factor 2 (3 entities in total)
Functional Keywords	protein interaction, inhibitor, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	74514.04
Authors	Muellers, S.N.,Allen, K.N. (deposition date: 2022-09-18, release date: 2023-09-27)
Primary citation	Muellers, S.N.,Allen, K.N.,Whitty, A. The benefit of cyclization: a comparison of cyclic and linear peptide inhibitors of the KEAP1/Nrf2 protein-protein interaction To Be Published,
Experimental method	X-RAY DIFFRACTION (2.82 Å)

Structure validation