8EJR
Kelch domain of human KEAP1 bound to Nrf2 linear peptide, Ac-GDPETGE-NH2
Summary for 8EJR
Entry DOI | 10.2210/pdb8ejr/pdb |
Descriptor | Kelch-like ECH-associated protein 1, Linear peptide from Nuclear factor erythroid 2-related factor 2 (3 entities in total) |
Functional Keywords | protein interaction, inhibitor, cyclic peptide, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 74526.05 |
Authors | |
Primary citation | Muellers, S.N.,Allen, K.N.,Whitty, A. The benefit of cyclization: a comparison of cyclic and linear peptide inhibitors of the KEAP1/Nrf2 protein-protein interaction To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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