8EHV

Kelch domain of human KEAP1 bound to Nrf2 cyclic peptide, c[DhA-GDPET(bAla)E]

Summary for 8EHV

• Entry DOI: 10.2210/pdb8ehv/pdb
• Descriptor: Kelch-like ECH-associated protein 1, cyclic peptide c[DhA-GDPET(bAla)E (3 entities in total)
• Functional Keywords: protein-protein interaction, inhibitor, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 74544.08

Authors

Muellers, S.N.,Allen, K.N. (deposition date: 2022-09-14, release date: 2023-09-20, Last modification date: 2023-11-15)

• Primary citation: Muellers, S.N.,Allen, K.N.,Whitty, A.; Machine-learning analysis of molecular dynamics simulations to elucidate the effect of strain and preorganization on conformational modes of motion in cyclic peptides; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.29 Å)