8EHV

Kelch domain of human KEAP1 bound to Nrf2 cyclic peptide, c[DhA-GDPET(bAla)E]

8EHV の概要

• エントリーDOI: 10.2210/pdb8ehv/pdb
• 分子名称: Kelch-like ECH-associated protein 1, cyclic peptide c[DhA-GDPET(bAla)E (3 entities in total)
• 機能のキーワード: protein-protein interaction, inhibitor, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 74544.08

構造登録者

Muellers, S.N.,Allen, K.N. (登録日: 2022-09-14, 公開日: 2023-09-20, 最終更新日: 2023-11-15)

• 主引用文献: Muellers, S.N.,Allen, K.N.,Whitty, A.; Machine-learning analysis of molecular dynamics simulations to elucidate the effect of strain and preorganization on conformational modes of motion in cyclic peptides; To Be Published,

実験手法

X-RAY DIFFRACTION (2.29 Å)