8EFP
CryoEM structure of GSDMB in complex with shigella IpaH7.8
Summary for 8EFP
Entry DOI | 10.2210/pdb8efp/pdb |
EMDB information | 28087 |
Descriptor | Probable E3 ubiquitin-protein ligase ipaH7.8, Gasdermin-B (2 entities in total) |
Functional Keywords | gsdmb, gsdmd, pyroptosis, ubiquitination, antimicrobial protein, transferase-lipid binding protein complex, transferase/lipid binding protein |
Biological source | Shigella flexneri More |
Total number of polymer chains | 2 |
Total formula weight | 112013.81 |
Authors | |
Primary citation | Wang, C.,Shivcharan, S.,Tian, T.,Wright, S.,Ma, D.,Chang, J.,Li, K.,Song, K.,Xu, C.,Rathinam, V.A.,Ruan, J. Structural basis for GSDMB pore formation and its targeting by IpaH7.8. Nature, 616:590-597, 2023 Cited by PubMed: 36991122DOI: 10.1038/s41586-023-05832-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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