8EFL
SR17018-bound mu-opioid receptor-Gi complex
Summary for 8EFL
Entry DOI | 10.2210/pdb8efl/pdb |
EMDB information | 28066 28069 28077 28085 28086 28088 |
Descriptor | Mu-type opioid receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total) |
Functional Keywords | mu-opioid receptor, g protein, fentanyl, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 240715.40 |
Authors | |
Primary citation | Zhuang, Y.,Wang, Y.,He, B.,He, X.,Zhou, X.E.,Guo, S.,Rao, Q.,Yang, J.,Liu, J.,Zhou, Q.,Wang, X.,Liu, M.,Liu, W.,Jiang, X.,Yang, D.,Jiang, H.,Shen, J.,Melcher, K.,Chen, H.,Jiang, Y.,Cheng, X.,Wang, M.W.,Xie, X.,Xu, H.E. Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185:4361-4375.e19, 2022 Cited by PubMed: 36368306DOI: 10.1016/j.cell.2022.09.041 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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