8EFJ

A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds

8EFJ の概要

• エントリーDOI: 10.2210/pdb8efj/pdb
• 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, (4P)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1H-indazol-1-yl]-N-methylthiophene-2-carboxamide, ... (4 entities in total)
• 機能のキーワード: c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43267.76

構造登録者

Park, H.,Feng, Y. (登録日: 2022-09-08, 公開日: 2023-09-20)

• 主引用文献: Park, H.,Feng, Y.; A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds; To Be Published,

実験手法

X-RAY DIFFRACTION (2.31 Å)