8EEC
Crystal structure of HPK1 citron-homology domain
Summary for 8EEC
| Entry DOI | 10.2210/pdb8eec/pdb |
| Descriptor | Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | beta-propeller, scaffolding, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 37969.14 |
| Authors | Wu, P.,Lehoux, I.,Wang, W. (deposition date: 2022-09-06, release date: 2024-03-27, Last modification date: 2024-10-09) |
| Primary citation | Chitre, A.S.,Wu, P.,Walters, B.T.,Wang, X.,Bouyssou, A.,Du, X.,Lehoux, I.,Fong, R.,Arata, A.,Chan, J.,Wang, D.,Franke, Y.,Grogan, J.L.,Mellman, I.,Comps-Agrar, L.,Wang, W. HPK1 citron homology domain regulates phosphorylation of SLP76 and modulates kinase domain interaction dynamics Nat Commun, 15:3725-, 2024 Cited by DOI: 10.1038/s41467-024-48014-9PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
