8E3I
CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal
Summary for 8E3I
Entry DOI | 10.2210/pdb8e3i/pdb |
EMDB information | 27866 |
Descriptor | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*CP*AP*UP*UP*AP*AP*AP*CP*AP*AP*C)-3'), ... (5 entities in total) |
Functional Keywords | mrna, 3'processing, polyadenylation, cpsf, rna binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 258286.71 |
Authors | Gutierrez, P.A.,Wei, J.,Sun, Y.,Tong, L. (deposition date: 2022-08-17, release date: 2023-01-18, Last modification date: 2024-06-12) |
Primary citation | Gutierrez, P.A.,Wei, J.,Sun, Y.,Tong, L. Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF. Rna, 28:1534-1541, 2022 Cited by PubMed: 36130077DOI: 10.1261/rna.079322.122 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.53 Å) |
Structure validation
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