8E15

A computationally stabilized hMPV F protein

8E15 の概要

• エントリーDOI: 10.2210/pdb8e15/pdb
• 分子名称: F2 protein, F1 protein with Fibritin peptide, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: human metapneumovirus, fusion protein, computational stabilization, viral protein
• 由来する生物種: Human metapneumovirus; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58715.36

構造登録者

Huang, J.,Gonzalez, K.,Mousa, J.,Strauch, E. (登録日: 2022-08-09, 公開日: 2023-04-12, 最終更新日: 2024-07-24)

• 主引用文献: Gonzalez, K.J.,Huang, J.,Criado, M.F.,Banerjee, A.,Tompkins, S.M.,Mousa, J.J.,Strauch, E.M.; A general computational design strategy for stabilizing viral class I fusion proteins.; Nat Commun, 15:1335-1335, 2024; PubMed: 38351001; DOI: 10.1038/s41467-024-45480-z

実験手法

X-RAY DIFFRACTION (2.41 Å)