8DZJ
Cryo-EM structure of Acidibacillus sulfuroxidans Cas12f in complex with sgRNA and target DNA
Summary for 8DZJ
Entry DOI | 10.2210/pdb8dzj/pdb |
EMDB information | 27801 |
Descriptor | OrfB_Zn_ribbon domain-containing protein, target DNA strand, Non-target DNA strand, ... (5 entities in total) |
Functional Keywords | crispr, cas12, gene editing, rna binding protein-rna-dna complex, rna binding protein/rna/dna |
Biological source | Acidibacillus sulfuroxidans More |
Total number of polymer chains | 5 |
Total formula weight | 191064.53 |
Authors | |
Primary citation | Wu, T.,Liu, C.,Zou, S.,Lyu, R.,Yang, B.,Yan, H.,Zhao, M.,Tang, W. An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity. Nat.Chem.Biol., 19:1384-1393, 2023 Cited by PubMed: 37400536DOI: 10.1038/s41589-023-01380-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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