8DYD

Crystal structure of human SDHA-SDHAF2-SDHAF4 assembly intermediate

8DYD の概要

• エントリーDOI: 10.2210/pdb8dyd/pdb
• 分子名称: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase assembly factor 2, mitochondrial, Succinate dehydrogenase assembly factor 4, mitochondrial, ... (10 entities in total)
• 機能のキーワード: sdha, flavoprotein, sdhaf2, sdhaf4, assembly intermediate, respiratory complex, oxidoreductase, electron transport
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 100559.51

構造登録者

Sharma, P.,Maklashina, E.,Cecchini, G.,Iverson, T.M. (登録日: 2022-08-04, 公開日: 2024-01-10, 最終更新日: 2024-02-07)

• 主引用文献: Sharma, P.,Maklashina, E.,Voehler, M.,Balintova, S.,Dvorakova, S.,Kraus, M.,Vanova, K.H.,Nahacka, Z.,Zobalova, R.,Boukalova, S.,Cunatova, K.,Mracek, T.,Ghayee, H.K.,Pacak, K.,Rohlena, J.,Neuzil, J.,Cecchini, G.,Iverson, T.M.; Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners.; Nat Commun, 15:473-473, 2024; PubMed: 38212624; DOI: 10.1038/s41467-023-44563-7

実験手法

X-RAY DIFFRACTION (1.52 Å)