8DY0

Crystal Structure of spFv GLK1 HL

Summary for 8DY0

• Entry DOI: 10.2210/pdb8dy0/pdb
• Descriptor: spFv GLK1 HL (2 entities in total)
• Functional Keywords: scfv, stapled scfv, spfv, germline scfv, single chain fv, scfv stabilizations, antibody, immune system
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 53122.73

Authors

Luo, J.,Boucher, L.E. (deposition date: 2022-08-03, release date: 2023-05-03, Last modification date: 2023-10-25)

• Primary citation: Boucher, L.E.,Prinslow, E.G.,Feldkamp, M.,Yi, F.,Nanjunda, R.,Wu, S.J.,Liu, T.,Lacy, E.R.,Jacobs, S.,Kozlyuk, N.,Del Rosario, B.,Wu, B.,Aquino, P.,Davidson, R.C.,Heyne, S.,Mazzanti, N.,Testa, J.,Diem, M.D.,Gorre, E.,Mahan, A.,Nanda, H.,Gunawardena, H.P.,Gervais, A.,Armstrong, A.A.,Teplyakov, A.,Huang, C.,Zwolak, A.,Chowdhury, P.,Cheung, W.C.,Luo, J.; "Stapling" scFv for multispecific biotherapeutics of superior properties.; Mabs, 15:2195517-2195517, 2023; PubMed: 37074212; DOI: 10.1080/19420862.2023.2195517

Experimental method

X-RAY DIFFRACTION (2.1 Å)