8DXB

HIV-1 reverse transcriptase/rilpivirine with bound fragment 5-fluoroindole-2-carboxylic acid at the NNRTI Adjacent site

Summary for 8DXB

Entry DOI	10.2210/pdb8dxb/pdb
Descriptor	Reverse transcriptase/ribonuclease H, p51 RT, 5-fluoroindole-2-carboxylic acid, ... (8 entities in total)
Functional Keywords	hiv-1 reverse transcriptase, transferase
Biological source	Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) More
Total number of polymer chains	2
Total formula weight	115667.15
Authors	Chopra, A.,Ruiz, F.X.,Bauman, J.D.,Arnold, E. (deposition date: 2022-08-02, release date: 2023-05-31, Last modification date: 2023-10-25)
Primary citation	Chopra, A.,Bauman, J.D.,Ruiz, F.X.,Arnold, E. Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. J.Med.Chem., 66:6013-6024, 2023 Cited by PubMed: 37115705 DOI: 10.1021/acs.jmedchem.2c01681 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation