8DX3

HIV-1 reverse transcriptase/rilpivirine with bound fragment 3-bromobenzylamine in the thumb subdomain

Summary for 8DX3

Entry DOI	10.2210/pdb8dx3/pdb
Descriptor	Reverse transcriptase/ribonuclease H, p51 RT, 1-(3-bromophenyl)methanamine, ... (9 entities in total)
Functional Keywords	hiv-1 reverse transcriptase, transferase
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	2
Total formula weight	115783.09
Authors	Chopra, A.,Ruiz, F.X.,Bauman, J.D.,Arnold, E. (deposition date: 2022-08-02, release date: 2023-05-31, Last modification date: 2023-10-25)
Primary citation	Chopra, A.,Bauman, J.D.,Ruiz, F.X.,Arnold, E. Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. J.Med.Chem., 66:6013-6024, 2023 Cited by PubMed: 37115705 DOI: 10.1021/acs.jmedchem.2c01681 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation