8DSK

Structure of the N358Y variant of serine hydroxymethyltransferase 8 in complex with PLP, glycine, and formyl tetrahydrofolate

Summary for 8DSK

Entry DOI	10.2210/pdb8dsk/pdb
Descriptor	Serine hydroxymethyltransferase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... (5 entities in total)
Functional Keywords	enzyme, complex, transferase
Biological source	Glycine max (soybean)
Total number of polymer chains	4
Total formula weight	220444.94
Authors	Korasick, D.A.,Beamer, L.J. (deposition date: 2022-07-22, release date: 2023-10-18, Last modification date: 2024-01-31)
Primary citation	Korasick, D.A.,Owuocha, L.F.,Kandoth, P.K.,Tanner, J.J.,Mitchum, M.G.,Beamer, L.J. Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance. Febs J., 291:323-337, 2024 Cited by PubMed: 37811683 DOI: 10.1111/febs.16971 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation