8DSG
P411-PFA carbene transferase
Summary for 8DSG
Entry DOI | 10.2210/pdb8dsg/pdb |
Descriptor | Cytochrome P450-BM3 variant P411-PFA, PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | cytochrome p450, carbene transferase, cyanomethylase, fluoroalkylation, oxidoreductase |
Biological source | Priestia megaterium |
Total number of polymer chains | 4 |
Total formula weight | 219841.37 |
Authors | Maggiolo, A.O.,Porter, N.J.,Zhang, J.,Arnold, F.H. (deposition date: 2022-07-22, release date: 2023-03-08, Last modification date: 2024-05-01) |
Primary citation | Zhang, J.,Maggiolo, A.O.,Alfonzo, E.,Mao, R.,Porter, N.J.,Abney, N.,Arnold, F.H. Chemodivergent C(sp 3 )-H and C(sp 2 )-H Cyanomethylation Using Engineered Carbene Transferases. Nat Catal, 6:152-160, 2023 Cited by PubMed: 36875868DOI: 10.1038/s41929-022-00908-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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