8DL4

S. CEREVISIAE CYP51 COMPLEXED WITH Courmarin-containing INHIBITOR

Summary for 8DL4

• Entry DOI: 10.2210/pdb8dl4/pdb
• Related: 4WMZ 5HS1
• Descriptor: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, 7-(diethylamino)-N-[(2S)-2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]-2-oxo-2H-1-benzopyran-3-carboxamide, ... (6 entities in total)
• Functional Keywords: courmarin, cyp51, sterol biosynthesis, oxidoreductase, oxidoreductase-oxidoreductase inhbitor complex, oxidoreductase/oxidoreductase inhbitor
• Biological source: Saccharomyces cerevisiae YJM789
• Total number of polymer chains: 1
• Total formula weight: 63417.63

Authors

Ruma, Y.N.,Keniya, M.V.,Tyndall, J.D.,Monk, B.C. (deposition date: 2022-07-06, release date: 2022-08-17, Last modification date: 2023-10-18)

• Primary citation: Benhamou, R.,Keniya, M.V.,Ruma, Y.N.,Fridman, M.,Tyndall, J.D.,Monk, B.C.; S. CEREVISIAE CYP51 COMPLEXED WITH Courmarin-containing INHIBITOR; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.91 Å)