8DF1

Chi3l1 bound by antibody C59

8DF1 の概要

• エントリーDOI: 10.2210/pdb8df1/pdb
• 分子名称: Chitinase-3-like protein 1, C59 Fab Heavy chain, C59 Fab Light chain, ... (6 entities in total)
• 機能のキーワード: chi3l1, fab, immunotherapeutic, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 524620.76

構造登録者

Wrapp, D.,McLellan, J.S. (登録日: 2022-06-21, 公開日: 2023-03-01, 最終更新日: 2023-10-25)

• 主引用文献: Li, L.,Wen, Y.,Wrapp, D.,Jeong, J.,Zhao, P.,Xiong, W.,Atkins, C.L.,Shan, Z.,Hui, D.,McLellan, J.S.,Zhang, N.,Ju, C.,An, Z.; A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.; Antib Ther, 6:1-12, 2023; PubMed: 36683763; DOI: 10.1093/abt/tbac027

実験手法

X-RAY DIFFRACTION (3.3 Å)