8DEU

Cryo-electron microscopy structure of Neisseria gonorrhoeae multidrug efflux pump MtrD with CASP peptide complex

Summary for 8DEU

• Entry DOI: 10.2210/pdb8deu/pdb
• EMDB information: 27399
• Descriptor: Efflux pump membrane transporter, CASP peptide, PHOSPHATIDYLETHANOLAMINE (3 entities in total)
• Functional Keywords: mtrd complex, multidrug efflux pump, neisseria gonorrhoeae, membrane protein
• Biological source: Neisseria gonorrhoeae; More
• Total number of polymer chains: 4
• Total formula weight: 362583.52

Authors

Lyu, M.,Yu, E.W. (deposition date: 2022-06-21, release date: 2022-09-14, Last modification date: 2022-11-09)

• Primary citation: Lyu, M.,Ayala, J.C.,Chirakos, I.,Su, C.C.,Shafer, W.M.,Yu, E.W.; Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump.; Microbiol Spectr, 10:e0299022-e0299022, 2022; PubMed: 36121287; DOI: 10.1128/spectrum.02990-22

Experimental method

ELECTRON MICROSCOPY (2.95 Å)