8D59
Crystal structure of human METTL1 in complex with SAM
Summary for 8D59
Entry DOI | 10.2210/pdb8d59/pdb |
Descriptor | tRNA (guanine-N(7)-)-methyltransferase, S-ADENOSYLMETHIONINE, GLYCEROL, ... (7 entities in total) |
Functional Keywords | cancer protein, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 31267.81 |
Authors | |
Primary citation | Ruiz-Arroyo, V.M.,Raj, R.,Babu, K.,Onolbaatar, O.,Roberts, P.H.,Nam, Y. Structures and mechanisms of tRNA methylation by METTL1-WDR4. Nature, 613:383-390, 2023 Cited by PubMed: 36599982DOI: 10.1038/s41586-022-05565-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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