8D4Y
C-terminal SANT-SLIDE domain of human Chromodomain-helicase-DNA-binding protein 4 (CHD4)
Summary for 8D4Y
Entry DOI | 10.2210/pdb8d4y/pdb |
Descriptor | Chromodomain-helicase-DNA-binding protein 4 (2 entities in total) |
Functional Keywords | chromodomain, sant, slide, nurd, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 98535.06 |
Authors | Moghaddas Sani, H.,Deshpande, C.N.,Panjikar, S.,Patel, K.,Mackay, J.P. (deposition date: 2022-06-03, release date: 2022-12-21, Last modification date: 2024-04-03) |
Primary citation | Zhong, Y.,Moghaddas Sani, H.,Paudel, B.P.,Low, J.K.K.,Silva, A.P.G.,Mueller, S.,Deshpande, C.,Panjikar, S.,Reid, X.J.,Bedward, M.J.,van Oijen, A.M.,Mackay, J.P. The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families. Nat Commun, 13:7524-7524, 2022 Cited by PubMed: 36473839DOI: 10.1038/s41467-022-35002-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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