8D4A
Cas12a2 quaternary complex
Summary for 8D4A
Entry DOI | 10.2210/pdb8d4a/pdb |
EMDB information | 27179 |
Descriptor | OrfB_Zn_ribbon domain-containing protein, RNA (41-MER), RNA (28-MER), ... (8 entities in total) |
Functional Keywords | cas12a2, crispr, nuclease, dna binding protein-rna-dna complex, dna binding protein/rna/dna |
Biological source | Sulfuricurvum sp. PC08-66 More |
Total number of polymer chains | 5 |
Total formula weight | 172074.41 |
Authors | Bravo, J.P.K.,Taylor, D.W. (deposition date: 2022-06-01, release date: 2023-01-18, Last modification date: 2024-06-12) |
Primary citation | Bravo, J.P.K.,Hallmark, T.,Naegle, B.,Beisel, C.L.,Jackson, R.N.,Taylor, D.W. RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature, 613:582-587, 2023 Cited by PubMed: 36599980DOI: 10.1038/s41586-022-05560-w PDB entries with the same primary citation |
Experimental method |
Structure validation
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