8D1W

Crystal structure of Plasmodium falciparum GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Summary for 8D1W

• Entry DOI: 10.2210/pdb8d1w/pdb
• Descriptor: Chaperone DnaK, 8-{[(2-chlorophenyl)methyl]amino}adenosine, SULFATE ION, ... (4 entities in total)
• Functional Keywords: atpase, chaperone
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 44959.33

Authors

Mrozek, A.,Chen, Y.,Antoshchenko, T.,Park, H.W.,Smil, D.,Zepeda, C.A.V. (deposition date: 2022-05-27, release date: 2023-05-31, Last modification date: 2023-10-25)

• Primary citation: Mrozek, A.,Park, H.W.; Targeting Plasmodium falciparum GRP78: nucleoside analogues as agents against the malaria chaperone; Frontiers in Molecular Bioscience, 2022

Experimental method

X-RAY DIFFRACTION (2.1 Å)