8CWO

Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map

Summary for 8CWO

Entry DOI	10.2210/pdb8cwo/pdb
Related	8CRX 8CVM 8CVO
EMDB information	27028
Descriptor	16S ribosomal RNA, 30S ribosomal protein S18, 30S ribosomal protein S20, ... (17 entities in total)
Functional Keywords	ribosome, sarecycline, acne, antibiotic
Biological source	Cutibacterium acnes More
Total number of polymer chains	15
Total formula weight	697950.32
Authors	Lomakin, I.B.,Devarkar, S.C.,Bunick, C.G. (deposition date: 2022-05-19, release date: 2023-03-15, Last modification date: 2024-06-12)
Primary citation	Lomakin, I.B.,Devarkar, S.C.,Patel, S.,Grada, A.,Bunick, C.G. Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51:2915-2930, 2023 Cited by PubMed: 36864821 DOI: 10.1093/nar/gkad103 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.84 Å)

Structure validation