8CVR
Human 20S proteasome with MG-132
Summary for 8CVR
Entry DOI | 10.2210/pdb8cvr/pdb |
EMDB information | 27013 27014 27015 27016 27017 27018 27019 |
Descriptor | Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (15 entities in total) |
Functional Keywords | proteolysis, protein degradation, complex, inhibitor, mg-132, mg132, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 28 |
Total formula weight | 736124.76 |
Authors | Zhao, J. (deposition date: 2022-05-18, release date: 2022-11-02, Last modification date: 2024-06-12) |
Primary citation | Zhao, J.,Makhija, S.,Zhou, C.,Zhang, H.,Wang, Y.,Muralidharan, M.,Huang, B.,Cheng, Y. Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119:e2207200119-e2207200119, 2022 Cited by PubMed: 35858375DOI: 10.1073/pnas.2207200119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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