8CVL

Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution

これはPDB形式変換不可エントリーです。

8CVL の概要

• エントリーDOI: 10.2210/pdb8cvl/pdb
• 分子名称: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (62 entities in total)
• 機能のキーワード: 70s ribosome, non-hydrolyzable, aminoacyl-trna, peptidyl-trna; formylation, pre-attack state, transpeptidation, peptidyl transferase center, nascent peptide exit tunnel, ribosome, ribosome-rna complex, ribosome/rna
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 114
• 化学式量合計: 4570642.99

構造登録者

Syroegin, E.A.,Aleksandrova, E.V.,Polikanov, Y.S. (登録日: 2022-05-18, 公開日: 2022-10-19, 最終更新日: 2023-11-15)

• 主引用文献: Syroegin, E.A.,Aleksandrova, E.V.,Polikanov, Y.S.; Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes.; Nat.Chem., 15:143-153, 2023; PubMed: 36316410; DOI: 10.1038/s41557-022-01073-1

実験手法

X-RAY DIFFRACTION (2.3 Å)