Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8CUH

Crystal structure of human TEAD2 complexed with its inhibitor TM2.

Summary for 8CUH
Entry DOI10.2210/pdb8cuh/pdb
DescriptorTranscriptional enhancer factor TEF-4, 4-[3-(2-cyclohexylethoxy)benzoyl]-N-phenylpiperazine-1-carboxamide (3 entities in total)
Functional Keywordstranscription factor, transcription-transcription inhibitor complex, transcription
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight55849.31
Authors
Liu, S.,Luo, X. (deposition date: 2022-05-17, release date: 2022-11-23, Last modification date: 2023-10-25)
Primary citationHu, L.,Sun, Y.,Liu, S.,Erb, H.,Singh, A.,Mao, J.,Luo, X.,Wu, X.
Discovery of a new class of reversible TEA-domain transcription factor inhibitors with a novel binding mode.
Elife, 11:-, 2022
Cited by
PubMed: 36398861
DOI: 10.7554/eLife.80210
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

221051

数据于2024-06-12公开中

PDB statisticsPDBj update infoContact PDBjnumon