8CUB
Crystal Structure of ABCG5/G8 in Complex with Cholesterol
Summary for 8CUB
Entry DOI | 10.2210/pdb8cub/pdb |
Descriptor | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, CHOLESTEROL (3 entities in total) |
Functional Keywords | abcg5, abcg8, membrane protein, cholesterol transporter, translocase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 303763.92 |
Authors | Rezaei, F.,Farhat, D.,Lee, J.Y. (deposition date: 2022-05-17, release date: 2022-08-31, Last modification date: 2023-10-18) |
Primary citation | Farhat, D.,Rezaei, F.,Ristovski, M.,Yang, Y.,Stancescu, A.,Dzimkova, L.,Samnani, S.,Couture, J.F.,Lee, J.Y. Structural Analysis of Cholesterol Binding and Sterol Selectivity by ABCG5/G8. J.Mol.Biol., 434:167795-167795, 2022 Cited by PubMed: 35988751DOI: 10.1016/j.jmb.2022.167795 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.05 Å) |
Structure validation
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