8CUB

Crystal Structure of ABCG5/G8 in Complex with Cholesterol

Summary for 8CUB

Entry DOI	10.2210/pdb8cub/pdb
Descriptor	ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, CHOLESTEROL (3 entities in total)
Functional Keywords	abcg5, abcg8, membrane protein, cholesterol transporter, translocase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	303763.92
Authors	Rezaei, F.,Farhat, D.,Lee, J.Y. (deposition date: 2022-05-17, release date: 2022-08-31, Last modification date: 2023-10-18)
Primary citation	Farhat, D.,Rezaei, F.,Ristovski, M.,Yang, Y.,Stancescu, A.,Dzimkova, L.,Samnani, S.,Couture, J.F.,Lee, J.Y. Structural Analysis of Cholesterol Binding and Sterol Selectivity by ABCG5/G8. J.Mol.Biol., 434:167795-167795, 2022 Cited by PubMed: 35988751 DOI: 10.1016/j.jmb.2022.167795 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.05 Å)

Structure validation