8CU0
12-mer DNA structure of ExBIM bound to RNaseH -modified DDD
Summary for 8CU0
Entry DOI | 10.2210/pdb8cu0/pdb |
Descriptor | Ribonuclease H, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*(OWR)P*CP*CP*G)-3'), 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | alkylation, base stacking, dna damage, h-bonding, exbim, dna |
Biological source | Halalkalibacterium halodurans More |
Total number of polymer chains | 5 |
Total formula weight | 57109.96 |
Authors | Pallan, P.S.,Egli, M. (deposition date: 2022-05-16, release date: 2022-08-31, Last modification date: 2023-10-18) |
Primary citation | Kellum Jr., A.H.,Pallan, P.S.,Nilforoushan, A.,Sturla, S.J.,Stone, M.P.,Egli, M. Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA. Chem.Res.Toxicol., 35:1903-1913, 2022 Cited by PubMed: 35973057DOI: 10.1021/acs.chemrestox.2c00165 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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