8CTZ
12-mer DNA structure of ExBIM & O6Me-G bound to RNase-H
Summary for 8CTZ
Entry DOI | 10.2210/pdb8ctz/pdb |
Descriptor | Ribonuclease H, DNA (5'-D(*CP*GP*CP*(6OG)P*AP*AP*TP*TP*(OWR)P*GP*CP*G)-3'), GLYCEROL, ... (8 entities in total) |
Functional Keywords | alkylation, base stacking, dna damage, h-bonding, o6-methyl-2'-deoxyguanosine, exbim, dna |
Biological source | Alkalihalobacillus halodurans More |
Total number of polymer chains | 5 |
Total formula weight | 57231.31 |
Authors | Pallan, P.S.,Egli, M. (deposition date: 2022-05-16, release date: 2022-08-31, Last modification date: 2023-10-18) |
Primary citation | Kellum Jr., A.H.,Pallan, P.S.,Nilforoushan, A.,Sturla, S.J.,Stone, M.P.,Egli, M. Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA. Chem.Res.Toxicol., 35:1903-1913, 2022 Cited by PubMed: 35973057DOI: 10.1021/acs.chemrestox.2c00165 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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