8CR5

Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta.

8CR5 の概要

• エントリーDOI: 10.2210/pdb8cr5/pdb
• 分子名称: Interleukin-12 subunit beta, Interleukin-12 receptor subunit beta-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: complex, inflammation, glycoprotein, immunity, cytokine
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69963.80

構造登録者

Merceron, R.,Bloch, Y.,Felix, J.,Savvides, S.N. (登録日: 2023-03-07, 公開日: 2024-02-07, 最終更新日: 2024-05-01)

• 主引用文献: Bloch, Y.,Felix, J.,Merceron, R.,Provost, M.,Symakani, R.A.,De Backer, R.,Lambert, E.,Mehdipour, A.R.,Savvides, S.N.; Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.; Nat.Struct.Mol.Biol., 31:591-597, 2024; PubMed: 38287195; DOI: 10.1038/s41594-023-01190-6

実験手法

X-RAY DIFFRACTION (2.15 Å)