8CF3
Crystal structure of S. aureus BlaR1 sensor domain in complex with cefepime
Summary for 8CF3
Entry DOI | 10.2210/pdb8cf3/pdb |
Related | 8C0P 8C0S |
Descriptor | Regulatory protein BlaR1, Cefepime (open) (3 entities in total) |
Functional Keywords | antibiotic resistance, beta-lactam sensor of staphylococcus aureus, mrsa, signaling protein |
Biological source | Staphylococcus aureus More |
Total number of polymer chains | 2 |
Total formula weight | 59885.44 |
Authors | |
Primary citation | Nguyen, V.T.,Birhanu, B.T.,Miguel-Ruano, V.,Kim, C.,Batuecas, M.,Yang, J.,El-Araby, A.M.,Jimenez-Faraco, E.,Schroeder, V.A.,Alba, A.,Rana, N.,Sader, S.,Thomas, C.A.,Feltzer, R.,Lee, M.,Fisher, J.F.,Hermoso, J.A.,Chang, M.,Mobashery, S. Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus. Nat.Chem.Biol., 2024 Cited by PubMed: 39060390DOI: 10.1038/s41589-024-01688-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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