8CF0

Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2

8CF0 の概要

• エントリーDOI: 10.2210/pdb8cf0/pdb
• 分子名称: DNA cross-link repair 1A protein, DIMETHYL SULFOXIDE, 9-chloranyl-1,4-dihydropyrazino[2,3-c]quinoline-2,3-dione, ... (5 entities in total)
• 機能のキーワード: snm1a, nuclease inhibitor, icl, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39524.80

構造登録者

Newman, J.A.,Yosaatmadja, Y.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O. (登録日: 2023-02-02, 公開日: 2024-02-21)

• 主引用文献: Newman, J.A.,Yosaatmadja, Y.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O.; Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2; To Be Published,

実験手法

X-RAY DIFFRACTION (1.76 Å)