8CBY
Crystal Structure of Anti-cortisol Fab in Complex with Cortisol
Summary for 8CBY
Entry DOI | 10.2210/pdb8cby/pdb |
Descriptor | anti-cortisol (17) Fab (light chain), anti-cortisol (17) Fab (heavy chain), (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, ... (4 entities in total) |
Functional Keywords | fab, cortisol, hapten, glucocorticoid, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 48636.18 |
Authors | Eronen, V.,Rouvinen, J.,Hakulinen, N. (deposition date: 2023-01-26, release date: 2023-05-10, Last modification date: 2024-02-07) |
Primary citation | Eronen, V.,Tullila, A.,Iljin, K.,Rouvinen, J.,Nevanen, T.K.,Hakulinen, N. Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids. J.Struct.Biol., 215:107966-107966, 2023 Cited by PubMed: 37100101DOI: 10.1016/j.jsb.2023.107966 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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