8CBY

Crystal Structure of Anti-cortisol Fab in Complex with Cortisol

Summary for 8CBY

Entry DOI	10.2210/pdb8cby/pdb
Descriptor	anti-cortisol (17) Fab (light chain), anti-cortisol (17) Fab (heavy chain), (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, ... (4 entities in total)
Functional Keywords	fab, cortisol, hapten, glucocorticoid, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	48636.18
Authors	Eronen, V.,Rouvinen, J.,Hakulinen, N. (deposition date: 2023-01-26, release date: 2023-05-10, Last modification date: 2024-02-07)
Primary citation	Eronen, V.,Tullila, A.,Iljin, K.,Rouvinen, J.,Nevanen, T.K.,Hakulinen, N. Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids. J.Struct.Biol., 215:107966-107966, 2023 Cited by PubMed: 37100101 DOI: 10.1016/j.jsb.2023.107966 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation