8C9U

Crystal structure of SARS-CoV-2 Mpro-Q189K mutant in complex with nirmatrelvir

This is a non-PDB format compatible entry.

Summary for 8C9U

• Entry DOI: 10.2210/pdb8c9u/pdb
• Descriptor: Non-structural protein 11, (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide (3 entities in total)
• Functional Keywords: mpro mutations main protease sars-cov-2, antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34200.01

Authors

El Kilani, H.,Hilgenfeld, R. (deposition date: 2023-01-23, release date: 2024-08-07)

• Primary citation: El Kilani, H.,Hilgenfeld, R.; Crystal structure of SARS-CoV-2 Mpro-Q189K mutant in complex with nirmatrelvir; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)