8C7W
Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304
Summary for 8C7W
Entry DOI | 10.2210/pdb8c7w/pdb |
Descriptor | Activin receptor type I, 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine, SULFATE ION, ... (5 entities in total) |
Functional Keywords | bmp signalling kinase inhibitor, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 35918.91 |
Authors | Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N. (deposition date: 2023-01-17, release date: 2023-02-08, Last modification date: 2024-02-07) |
Primary citation | Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N. Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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