8C7W

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304

Summary for 8C7W

• Entry DOI: 10.2210/pdb8c7w/pdb
• Descriptor: Activin receptor type I, 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine, SULFATE ION, ... (5 entities in total)
• Functional Keywords: bmp signalling kinase inhibitor, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35918.91

Authors

Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N. (deposition date: 2023-01-17, release date: 2023-02-08, Last modification date: 2024-02-07)

• Primary citation: Cros, J.,Williams, E.P.,Sweeney, M.N.,Smil, D.,Gonzalez-Alvarez, H.,Al-awar, R.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.26 Å)