8C6N
Human protein kinase CK2 alpha in complex with CK2-TN03
Summary for 8C6N
Entry DOI | 10.2210/pdb8c6n/pdb |
Related | 8C6L 8C6M |
Descriptor | Casein kinase II subunit alpha, (2~{Z},5~{Z})-5-[(4-methoxy-3-oxidanyl-phenyl)methylidene]-2-phenylimino-1,3-thiazolidin-4-one, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinase domain, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40768.38 |
Authors | |
Primary citation | Cazzanelli, G.,Dalle Vedove, A.,Broso, F.,Burigotto, M.,Aiello, G.,Ruzzene, M.,Tiberi, L.,Fava, L.,Quattrone, A.,Lolli, G. Switching off CK2-mediated activation of survivin offers new therapeutic opportunities in neuroblastoma to be published, |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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