8C5S
Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer RNA, pppGpGpUpApApApU (IC7)
Summary for 8C5S
Entry DOI | 10.2210/pdb8c5s/pdb |
Related | 6YMV 6YMW 8AP1 8ATT 8ATV 8ATW 8C5U 8Q63 |
EMDB information | 10845 10846 15556 15662 15664 15665 16442 16443 18183 |
Descriptor | Mitochondrial transcription factor 1, DNA-directed RNA polymerase, mitochondrial, Non-Template DNA (37-MER), ... (6 entities in total) |
Functional Keywords | gene transcription, polymerase, rdrp, mtf1, rpo41, polrmt, mtrnap, dna, transcription initiation, rna polymerase, mitochondria, transcription, ic7 |
Biological source | Saccharomyces cerevisiae S288C More |
Total number of polymer chains | 5 |
Total formula weight | 209624.00 |
Authors | Goovaerts, Q.,Shen, J.,Patel, S.S.,Das, K. (deposition date: 2023-01-10, release date: 2023-08-30, Last modification date: 2023-11-01) |
Primary citation | Goovaerts, Q.,Shen, J.,De Wijngaert, B.,Basu, U.,Patel, S.S.,Das, K. Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622:872-879, 2023 Cited by PubMed: 37821701DOI: 10.1038/s41586-023-06643-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.75 Å) |
Structure validation
Download full validation report