8C51

Trypanosoma brucei IMP dehydrogenase (cyto) crystallized in High Five cells revealing native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo

Summary for 8C51

Entry DOI	10.2210/pdb8c51/pdb
Related	8C51 8C53
Descriptor	Inosine-5'-monophosphate dehydrogenase, GUANOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	imp dehydrogenase, purine biosynthetic enzyme, native cofactors, transferase
Biological source	Trypanosoma brucei
Total number of polymer chains	2
Total formula weight	113219.46
Authors	Lahey-Rudolph, J.M.,Schoenherr, R.,Boger, J.,Harms, M.,Kaiser, J.,Nachtschatt, S.,Wobbe, M.,Duden, R.,Koenig, P.,Bourenkov, G.,Schneider, T.,Redecke, L. (deposition date: 2023-01-06, release date: 2024-01-17, Last modification date: 2024-03-06)
Primary citation	Schonherr, R.,Boger, J.,Lahey-Rudolph, J.M.,Harms, M.,Kaiser, J.,Nachtschatt, S.,Wobbe, M.,Duden, R.,Konig, P.,Bourenkov, G.,Schneider, T.R.,Redecke, L. A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15:1709-1709, 2024 Cited by PubMed: 38402242 DOI: 10.1038/s41467-024-45985-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation