8C44

HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR

Summary for 8C44

• Entry DOI: 10.2210/pdb8c44/pdb
• EMDB information: 16416
• Descriptor: PfEMP1, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total)
• Functional Keywords: plasmodium falciparum, cerebral malaria, pfemp1, epcr, cell adhesion
• Biological source: Plasmodium falciparum HB3; More
• Total number of polymer chains: 2
• Total formula weight: 165585.94

Authors

Raghavan, S.S.R.,Lavstsen, T.,Wang, K.T. (deposition date: 2022-12-31, release date: 2023-08-16, Last modification date: 2023-12-27)

• Primary citation: Rajan Raghavan, S.S.,Turner, L.,Jensen, R.W.,Johansen, N.T.,Jensen, D.S.,Gourdon, P.,Zhang, J.,Wang, Y.,Theander, T.G.,Wang, K.,Lavstsen, T.; Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.; Structure, 31:1174-1183.e4, 2023; PubMed: 37582356; DOI: 10.1016/j.str.2023.07.011

Experimental method

ELECTRON MICROSCOPY (3.2 Å)